Table 3. Effects of Biotona skin food on cell viability, pro-collagen typeⅠC peptide production and MMP-1 secretion of HS68 cell and HaCaT cell

Biotona skin food (μg/mL)	HaCaT cell		Hs68 cell
	Cell viability (%)	MMP-1 (ng/mL)	Cell viability (%)	pro-collagen type I C (ng/mL)
Control	100.00±3.25	0.54±0.05	100.00±6.94	559.84±28.26
62.5	98.25±4.35	0.93±0.04	112.20±0.81	743.68±96.68*
125	102.55±1.27	0.89±0.07	105.08±0.38	588.71±36.41
250	106.38±4.80	0.98±0.06	113.06±0.50	569.32±83.09
500	110.78±4.20*	1.08±0.14	107.75±2.35	614.11±91.80
EGCG	124.28±3.59***	0.07±0.03***	124.38±3.25***	695.14±42.09***

p<0.05,
p<0.01,
p<0.001.
EGCG, Eepigallocathechingallate was used as positive control.