Table 10. Effects of pregnagen formula on cell viability, pro-collagen type I C peptide production and MMP-1 secretion of HS68 cell

Prenagen (μg/mL)	Hs68 cells
	Cell viability (%)	MMP-1 (ng/mL)	pro-collagen type I C (ng/mL)
Control	100.00±5.46	4.10±0.08	1,269.47±72.75
25	103.68±0.51	1.90±0.05***	1,316.07±88.22
50	105.12±0.32	2.08±0.21***	1,406.66±167.43
100	92.17±0.81	1.46±0.10***	1,554.54±140.22*
200	97.56±0.81	1.58±0.20***	1,612.03±2.98***

p<0.05,
p<0.01,
p<0.001.