Table 2 The screening of probiotic strains using by in vitro assays such as small animals or rodent models

The most recently published articles The screening of intervention The functionality of probiotics
Sodhi et al. (2012) Tissue-specific knock-out Closely related innate and adaptive immunity
Martin et al. (2008) Humanized mice Hosting complex microbiota
Verdu and Collins (2004) Axenic mice
Eaton et al. (2011) Monocolonized mice
Le Roy et al. (2013) Microbiota transplantation
Henao-Mejia et al. (2012) Co-housing
Viaud et al. (2013) Selective antibiotic treatment
Helm and Burks (2002) Transgenic mice Physiological relevance for humans
Kim et al. (2014) Allergy, inflammation Responsiveness to many infectious, immune and other disorders
Kikuchi et al. (2014) Bacteria, virus, fungi and parasites pathogens
Kwon et al. (2013) Neurologic disorders
Hsiao et al. (2013) Stress, cognitive functions
Sodhi et al. (2013) Conditional knock-out Sharing of similar immune response types
Source: Papadimitriou et al., 2015