Table 13 An assessment of the changes in plasma coagulation values affected by the 90-day oral administration of 7%-GNANA, a test substance to the male and female rats (n=10)

Tests	Groups (mg/kg/day)a)
	G1%			G2			G3			G4
	Male	Female		Male	Female		Male	Female		Male	Female
PT (sec)	8.54±0.370	8.67±0.509		8.66±0.354	8.94±0.448		8.33±0.341	8.88±0.281		8.49±0.293	8.78±0.369
APTT(sec)	17.6±1.52	17.0±1.50		16.7±1.53	17.0±1.34		17.4±1.89	16.6±1.19		18.0±1.89	16.6±2.14
No. of animals	10	10		10	10		10	10		10	10

%: Control group (G1), Low-dose group (G2: 1,250 mg/10 mL/day), Medium-dose group (G3: 2,500 mg/10 mL/day)