Table 7 A clinical investigation of the ophthalmic findings affected by the 90-day oral administration of 23%-GNANA, a test substance to the male and female rats (n=10)

Sites^a	Findings	Groups (mg/kg/day)^b)
		G1 (0)^%		G2 (1,250)		G3 (2,500)		G4 (5,000)
		Male	Female	Male	Female	Male	Female	Male	Female
Left eye	Normal	0 / 5^*	0 / 5^*	0 / 5	0 / 5	0 / 5	0 / 5	0 / 5	0 / 5
Right eye	Normal	0 / 5^*	0 / 5^*	0 / 5	0 / 5	0 / 5	0 / 5	0 / 5	/ 5

^a: Number of animals with the finding / Number of animals examined
^*: Represents a significant difference at p<0.05 level compared with the vehicle control.
%: Control group (G1), Low-dose group (G2: 1,250 mg/10 mL/day), Medium-dose group (G3: 2,500 mg/10 mL/day), High-dose group (G4: 5,000 mg/10 mL/day)