Table 3 Table of severity values for statistical analysis by item of urinalysis signs during the 90 days oral administration of 23%-GNANA, a test substance to the rats

Severity 0 1 2 3 4 5
GLU - +/- 1+ 2+ 3+ 4+
BIL - +/- 1+ 2+ 3+
KET - +/- 1+ 2+ 3+ 4+
SG (Specific gravity) 1.005 1.010 1.015 1.020 1.025 1.030
PRO - +/- 1+ 2+ 3+ 4+
pH 6.5 7.0 7.5 8.0 8.5 >=9.0
URO (EU/dL) 0.2 1 2 4 >=8
NIT - +
OB (μlmol/L) - +/- 1+ 2+ 3+
LEU - +/- 1+ 2+ 3+
RBC 0 +/- 1+ 2+ 3+
WBC 0 +/- 1+ 2+ 3+
Epithelial cell 0 +/- 1+ 2+ 3+
Cast 0 +/- 1+ 2+ 3+
GLU (glucose), BIL (bilirubin), KET (ketone body), LEU (leukocyte), OB (occult blood), PRO (protein), URO (urobilinogen), NIT (nitrite), SG (specific gravity)