Table 16 An assessment of the changes in necropsy findings affected by the 90-day oral administration of 23%-GNANA, a test substance to the male and female rats (n=10)

Organs	Observed signs	Groups (mg/kg/day)a)
		G1 (0)%		G2 (1,250)		G3 (2,500)		G4 (5,000)
		Male	Female	Male	Female	Male	Female	Male	Female
Thymus	Redness	1		1		0		0
Testis(R)	Aatropy	0		0		0		1
Uterus	Retention of clear fluid		0		0		0		2
Adrenal(R)	Aatropy		0		0		0		1
No. of animals		10	10	10	10	10	10	10	10

%: Control group (G1), Low-dose group (G2: 1,250 mg/10 mL/day), Medium-dose group (G3: 2,500 mg/10 mL/day), High-dose group (G4: 5,000 mg/10 mL/day)