Table 10 An assessment of the changes in urine volume and color affected by the 90-day oral administration of 23%-GNANA, a test substance to the male and female rats (n=10)

Tests	Groups (mg/kg/day)a)
	G1 (0)%		G2 (1,250)		G3 (2,500)		G4 (5,000)
	Male	Female	Male	Female	Male	Female	Male	Female
Volume (mL)	12.8±1.89*	9.0±2.24*	11.4±3.23	9.2±4.34	12±2.74	7.8±4.15	17.1±2.25	9.8±3.98
Color-yellow	5*	5*	5	5	5	5	5	5
No. of animals	5*	5*	5	5	5	5	5	5

^*: Represents a significant difference at p<0.05 level compared with the vehicle control.
%: Control group (G1), Low-dose group (G2: 1,250 mg/10 mL/day), Medium-dose group (G3: 2,500 mg/10 mL/day), High-dose group (G4: 5,000 mg/10 mL/day)